Model organism zebrafish
2010-05-17
majifen
950
It is easy to raise, exquisite and lively, and has certain ornamental value. It is an entry-level species often chosen by beginners. The embryo develops outside the mother's body and is transparent, making it easy to observe. Weinstein's study found that zebrafish gridlock mutants behave similarly to human congenital arterial vasoconstriction; Drummond et al. found that the phenotype of doublebubble mutants is similar to the symptoms of human autosomal dominant polycystic kidney disease. Professor Hopkins identified 11 zebrafish mutants that develop polycystic kidney disease; Fleer and elipsa mutants show renal and eye dysplasia, similar to human Senior-Loken syndrome; sapje mutant is a model of human myasthenia.
